N-Glycan biosynthesis
PAG Title | N-Glycan biosynthesis |
PAG ID | WAG001630 |
Type | P |
Source Link | KEGG |
Publication Reference | NA |
PAG Description | N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glycans are covalently attached to asparagine with the consensus sequence of Asn-X-Ser/Thr by an N-glycosidic bond, Glcc b1- Asn. Biosynthesis of N-glycans begins on the cytoplasmic face of the ER membrane with the transferase reaction of UDP-Glcc and the lipid-like precursor P-Dol (dolichol phosphate) to generate Glcc a1- PP-Dol. After sequential addition of monosaccharides by ALG glycosyltransferases [MD: |
Species | Homo sapiens |
Quality Metric Scores | nCoCo Score: 552 |
Information Content | Rich |
Other IDs | hsa00510 |
Base PAG ID | WAG001630 |
Human Phenotyte Annotation | |
Curator | PAGER curation team |
Curator Contact | PAGER-contact@googlegroups.com |
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