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N-Glycan biosynthesis

PAG Title N-Glycan biosynthesis
PAG ID WAG001630
Type P
Source Link KEGG
Publication Reference NA
PAG Description N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glycans are covalently attached to asparagine with the consensus sequence of Asn-X-Ser/Thr by an N-glycosidic bond, Glcc b1- Asn. Biosynthesis of N-glycans begins on the cytoplasmic face of the ER membrane with the transferase reaction of UDP-Glcc and the lipid-like precursor P-Dol (dolichol phosphate) to generate Glcc a1- PP-Dol. After sequential addition of monosaccharides by ALG glycosyltransferases [MD:
Species Homo sapiens
nCoCo Score 552
Base PAG ID WAG001630
Human Phenotyte Annotation
Curator PAGER curation team
Curator Contact PAGER-contact@googlegroups.com
Gene ID Gene symbol Gene name RP_score
Gene A Gene B Source SCORE

Gene A Gene B Mechanism Source
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